Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro

• Main Authors: Dong-Hyun Youn (Author), Jinbong Park (Author), Hye-Lin Kim (Author), Yunu Jung (Author), JongWook Kang (Author), Seona Lim (Author), Gahee Song (Author), Hyun Jeong Kwak (Author), Jae-Young Um (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Benign prostate hyperplasia (BPH) is a common disease in elderly men, characterized by proliferated prostate and urinary tract symptoms. The hormonal cascade starting by the action of 5-alpha-reductase (5AR) is known to be one of the pathways responsible for the pathogenesis of BPH. Present investig...