PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

• Main Authors: Xiao-Feng Li (Author), Sha Wu (Author), Qi Yan (Author), Yuan-Yuan Wu (Author), He Chen (Author), Su-Qin Yin (Author), Xin Chen (Author), Hua Wang (Author), Jun Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and subsequent destruction of adjacent articular cartilage and bone. In our previous work we showed that phosphatase and tension homolog deleted on chromosome 10 (PTEN) contributes to the activation of fibroblast-li...