Addition of Sodium Pyruvate to Stored Red Blood Cells Attenuates Liver Injury in a Murine Transfusion Model

• Main Authors: Sha Xia (Author), Gan Chen (Author), Bo Wang (Author), Yujing Yin (Author), Zhenwei Sun (Author), Jingxiang Zhao (Author), Penglong Li (Author), Lian Zhao (Author), Hong Zhou (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RBCs undergo numerous changes during storage and stored RBCs may induce adverse effects, ultimately resulting in organ injury in transfusion recipients. We tested the hypothesis that the addition of SP to stored RBCs would improve the quality of the stored RBCs and mitigate liver injury after transf...