PathwayTMB: A pathway-based tumor mutational burden analysis method for predicting the clinical outcome of cancer immunotherapy

• Main Authors: Xiangmei Li (Author), Yalan He (Author), Ying Jiang (Author), Bingyue Pan (Author), Jiashuo Wu (Author), Xilong Zhao (Author), Junling Huang (Author), Qian Wang (Author), Liang Cheng (Author), Junwei Han (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunotherapy has become one of the most promising therapy methods for cancer, but only a small number of patients are responsive to it, indicating that more effective biomarkers are urgently needed. This study developed a pathway analysis method, named PathwayTMB, to identify genomic mutation pathw...