Role of Leukotrienes on Protozoan and Helminth Infections

• मुख्य लेखकों: Alexandre P. Rogerio (लेखक), Fernanda F. Anibal (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2012-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Leukotrienes (LTs), formed by the 5-lipoxygenase-(5-LO-) catalyzed oxidation of arachidonic acid, are lipid mediators that have potent proinflammatory activities. Pharmacologic or genetic inhibition of 5-LO biosynthesis in animals is associated with increased mortality and impaired clearance of bact...