Epigenetic Scanning of <i>KEAP1</i> CpG Sites Uncovers New Molecular-Driven Patterns in Lung Adeno and Squamous Cell Carcinomas

• Main Authors: Federico Pio Fabrizio (Author), Tommaso Mazza (Author), Stefano Castellana (Author), Angelo Sparaneo (Author), Lucia Anna Muscarella (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The KEAP1/NRF2 (Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2) pathway modulates detoxification processes and participates in the resistance of solid tumors to therapy. Scientific evidence about the presence of genetic and epigenetic abnormalities of the...