Synthesis and Evaluation of Some New 4<i>H</i>-Pyran Derivatives as Antioxidant, Antibacterial and Anti-HCT-116 Cells of CRC, with Molecular Docking, Antiproliferative, Apoptotic and ADME Investigations

• Asıl Yazarlar: Nahed N. E. El-Sayed (Yazar), Magdi E. A. Zaki (Yazar), Sami A. Al-Hussain (Yazar), Abir Ben Bacha (Yazar), Malika Berredjem (Yazar), Vijay H. Masand (Yazar), Zainab M. Almarhoon (Yazar), Hanaa S. Omar (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Colorectal cancer oncogenesis is linked to dysbiosis, oxidative stress and overexpression of CDK2. The 4<i>H</i>-pyran scaffold is considered an antitumoral, antibacterial and antioxidant lead as well as a CDK2 inhibitor. Herein, certain 4<i>H</i>-pyran derivatives were evalu...