Pioglitazone Represents an Effective Therapeutic Target in Preventing Oxidative/Inflammatory Cochlear Damage Induced by Noise Exposure

• Main Authors: Fabiola Paciello (Author), Anna Rita Fetoni (Author), Rolando Rolesi (Author), Matthew B. Wright (Author), Claudio Grassi (Author), Diana Troiani (Author), Gaetano Paludetti (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent progress in hearing loss research has provided strong evidence for the imbalance of cellular redox status and inflammation as common predominant mechanisms of damage affecting the organ of Corti including noise induced hearing loss. The discovery of a protective molecule acting on both mechan...