Impact of polymorphisms of pharmacokinetics‐related genes and the inflammatory response on the metabolism of voriconazole

Impact of polymorphisms of pharmacokinetics‐related genes and the inflammatory response on the metabolism of voriconazole

Abstract The effects of inflammatory responses and polymorphisms of the genes encoding cytochrome P450 (CYP) (CYP2C19 and CYP3A5), flavin‐containing monooxygenase 3 (FMO3), pregnane X receptor (NR1I2), constitutive androstane receptor (NR1I3), and CYP oxidoreductase (POR) on the ratio of voriconazol...

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Main Authors: Naoya Aiuchi (Author), Junichi Nakagawa (Author), Hirotake Sakuraba (Author), Takenori Takahata (Author), Kosuke Kamata (Author), Norihiro Saito (Author), Kayo Ueno (Author), Masahiro Ishiyama (Author), Kazufumi Yamagata (Author), Hiroyuki Kayaba (Author), Takenori Niioka (Author)
Format: Book
Published: Wiley, 2022-04-01T00:00:00Z.
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