Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells

• Autori principali: Ying Yang (Autore), Guiming Guo (Autore), Wei Zhou (Autore), Yunxuan Ge (Autore), Zheng Fan (Autore), Qingquan Liu (Autore), Yue Gao (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Bavachin (BV), a natural flavonoid compound derived from Psoralea corylifolia L, has been reported to be a potential hepatotoxin. Our previous studies have found that BV can induce endoplasmic reticulum (ER) stress-related cell apoptosis, but the molecular mechanism underlying BV-induced ER stress r...