A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila

• Main Authors: Laura Palanker Musselman (Author), Jill L. Fink (Author), Kirk Narzinski (Author), Prasanna Venkatesh Ramachandran (Author), Sumitha Sukumar Hathiramani (Author), Ross L. Cagan (Author), Thomas J. Baranski (Author)
• Format: Book
• Published: The Company of Biologists, 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Insulin-resistant, 'type 2' diabetes (T2D) results from a complex interplay between genes and environment. In particular, both caloric excess and obesity are strongly associated with T2D across many genetic backgrounds. To gain insights into how dietary excess affects insulin resis...