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Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor

Abstract Despite advances in HIV‐1 management with antiretroviral therapy, drug resistance and toxicities with multidrug regimens can result in treatment failure. Hence, there is a continuing demand for antiretroviral agents (ARVs) with novel mechanisms of action. Maturation inhibitors inhibit HIV‐1...

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Main Authors: Samit R. Joshi (Author), Disala Fernando (Author), Stephanie Igwe (Author), Litza McKenzie (Author), Anu S. Krishnatry (Author), Fiona Halliday (Author), Joyce Zhan (Author), Thomas J. Greene (Author), Jianfeng Xu (Author), Geraldine Ferron‐Brady (Author), Max Lataillade (Author), Sherene Min (Author)
Format: Book
Published: Wiley, 2020-12-01T00:00:00Z.
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