Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan

• Main Authors: Naveen Chella (Author), Nalini Shastri (Author), Rama Rao Tadikonda (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2012-10-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The aim of this study was to improve the dissolution rate of the poorly soluble drug valsartan by delivering the drug as a liquisolid compact. Liquisolid compacts were prepared using propylene glycol as solvent, Avicel PH102 as carrier, and Aerosil 200 as the coating material. The crystallinity of t...