Small molecule KDM4s inhibitors as anti-cancer agents

• Main Authors: Hongzhi Lin (Author), Qihang Li (Author), Qi Li (Author), Jie Zhu (Author), Kai Gu (Author), Xueyang Jiang (Author), Qianqian Hu (Author), Feng Feng (Author), Wei Qu (Author), Yao Chen (Author), Haopeng Sun (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...