Small molecule KDM4s inhibitors as anti-cancer agents

• المؤلفون الرئيسيون: Hongzhi Lin (مؤلف), Qihang Li (مؤلف), Qi Li (مؤلف), Jie Zhu (مؤلف), Kai Gu (مؤلف), Xueyang Jiang (مؤلف), Qianqian Hu (مؤلف), Feng Feng (مؤلف), Wei Qu (مؤلف), Yao Chen (مؤلف), Haopeng Sun (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...