Search for angiotensin II receptor antagonists among 4-aryl-n-(aryl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-imine derivatives

• Main Authors: Iryna Drapak (Author), Borys Zimenkovsky (Author), Lina Perekhoda (Author), Мargarita Suleyman (Author), Hanna Yeromina (Author), Natalia Skaletska (Author), Natalya Seredynska (Author), Anatoly Demchenko (Author)
• Format: Book
• Published: Pensoft Publishers, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of study was to find potential antihypertensive and cardiotropic drugs among new 4-aryl-N-(aryl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-imines. Materials and methods: The target compounds were synthesized by condensation asymmetrical substituted thioureas with α-bromo-4-R1-acetophenone...