Decrease in the Kainate-Induced Wet Dog Shake Behavior in Genetically Epilepsy-Prone Rats: Possible Involvement of an Impaired Synaptic Transmission to the 5-HT2A Receptor

• Main Authors: Eun-Joo Shin (Author), Ji Hoon Jeong (Author), Yoon Hee Chung (Author), Tae-Woo Kim (Author), Chan Young Shin (Author), Won-Ki Kim (Author), Kwang-Ho Ko (Author), Hyoung-Chun Kim (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Genetically epilepsy-prone rats (GEPR-9s) were derived from Sprague-Dawley rats (SD). The number of kainate-induced wet dog shake behavior (WDS) responses was found to decrease significantly in GEPR-9s compared to SD. WDS responses were potentiated by 5-hydroxytryptophan or 2,5-dimethoxy-...