Platelet activating factor contributes to vascular leak in acute dengue infection.

• Main Authors: Chandima Jeewandara (Author), Laksiri Gomes (Author), N Wickramasinghe (Author), Danuta Gutowska-Owsiak (Author), Dominic Waithe (Author), S A Paranavitane (Author), N L A Shyamali (Author), Graham S Ogg (Author), Gathsaurie Neelika Malavige (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Although plasma leakage is the hallmark of severe dengue infections, the factors that cause increased vascular permeability have not been identified. As platelet activating factor (PAF) is associated with an increase in vascular permeability in other diseases, we set out to investigate it...