Identification of novel anti-CD16a antibody clones for the development of effective natural killer cell engagers

• Главные авторы: Bill Liao (Автор), Christine Tumanut (Автор), Lin Li (Автор), Adam Corper (Автор), Dilip Challa (Автор), Alex Chang (Автор), Hydari Begum (Автор), Elinaz Farokhi (Автор), Catherine Woods (Автор), Xiaomin Fan (Автор)
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• Опубликовано: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Предметы: article
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Natural killer (NK) cells are key players in human innate immunity. Cell engager antibody formats that recruit and activate NK cells more effectively have emerged as a promising immunotherapy approach to target cancer cells through more effective antibody-dependent cell-mediated cytotoxicity (ADCC)....