Identification of novel anti-CD16a antibody clones for the development of effective natural killer cell engagers

• Main Authors: Bill Liao (Author), Christine Tumanut (Author), Lin Li (Author), Adam Corper (Author), Dilip Challa (Author), Alex Chang (Author), Hydari Begum (Author), Elinaz Farokhi (Author), Catherine Woods (Author), Xiaomin Fan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Natural killer (NK) cells are key players in human innate immunity. Cell engager antibody formats that recruit and activate NK cells more effectively have emerged as a promising immunotherapy approach to target cancer cells through more effective antibody-dependent cell-mediated cytotoxicity (ADCC)....