Administration of Glutaredoxin-1 Attenuates Liver Fibrosis Caused by Aging and Non-Alcoholic Steatohepatitis

• Үндсэн зохиолчид: Yuko Tsukahara (Зохиогч), Beatriz Ferran (Зохиогч), Erika T. Minetti (Зохиогч), Brian S. H. Chong (Зохиогч), Adam C. Gower (Зохиогч), Markus M. Bachschmid (Зохиогч), Reiko Matsui (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Liver fibrosis is a sign of non-alcoholic fatty liver disease progression towards steatohepatitis (NASH) and cirrhosis and is accelerated by aging. Glutaredoxin-1 (Glrx) controls redox signaling by reversing protein <i>S</i>-glutathionylation, induced by oxidative stress, and its deletio...