Altered Function and Expression of ABC Transporters at the Blood-Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice

• Prif Awduron: Li Liu (Awdur), Mingxing Miao (Awdur), Yang Chen (Awdur), Zhongjian Wang (Awdur), Binbin Sun (Awdur), Xiaodong Liu (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

This study investigated alterations in the function and expression of P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) at the blood-brain barrier (BBB) of acute liver failure (ALF) mice and its clinical significance. ALF mice were d...