Proline hydroxylase 2 (PHD2) promotes brown adipose thermogenesis by enhancing the hydroxylation of UCP1

• Main Authors: Fan Li (Author), Fenglin Zhang (Author), Xin Yi (Author), Lu Lu Quan (Author), Xiaohua Yang (Author), Cong Yin (Author), Zewei Ma (Author), Ruifan Wu (Author), Weijie Zhao (Author), Mingfa Ling (Author), Limin Lang (Author), Abdelaziz Hussein (Author), Shengchun Feng (Author), Yiming Fu (Author), Junfeng Wang (Author), Shuyi Liang (Author), Canjun Zhu (Author), Lina Wang (Author), Xiaotong Zhu (Author), Ping Gao (Author), Qianyun Xi (Author), Yongliang Zhang (Author), Lin Zhang (Author), Gang Shu (Author), Qingyan Jiang (Author), Songbo Wang (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Brown adipose tissue (BAT) plays a crucial role in regulating non-shivering thermogenesis under cold exposure. Proline hydroxylases (PHDs) were found to be involved in adipocyte differentiation and lipid deposition. However, the effects of PHDs on regulatory mechanisms of BAT thermogenesi...