Resveratrol Downmodulates Neutrophil Extracellular Trap (NET) Generation by Neutrophils in Patients with Severe COVID-19

• Main Authors: Milena M. de Souza Andrade (Author), Vinicius N. C. Leal (Author), Iara G. Fernandes (Author), Sarah C. Gozzi-Silva (Author), Danielle R. Beserra (Author), Emily A. Oliveira (Author), Franciane M. E. Teixeira (Author), Tatiana M. Yendo (Author), Maria da Glória T. Sousa (Author), Walcy R. Teodoro (Author), Luana de M. Oliveira (Author), Ricardo W. Alberca (Author), Valéria Aoki (Author), Alberto J. S. Duarte (Author), Maria N. Sato (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The formation of microthrombi in lung autopsies indicates the involvement of NETs in the immunopathogenesis of severe COVID-19. Therefore, supplements inhibiting NET formation, in association with drugs with fewer adverse effects, should be a relevant strategy to attenuate the disease. Resveratrol (...