Modulation of cell proliferation, survival and gene expression by RAGE and TLR signaling in cells of the innate and adaptive immune response: role of p38 MAPK and NF-KB

• Main Authors: Marcell Costa de MEDEIROS (Author), Sabrina Cruz Tfaile FRASNELLI (Author), Alliny de Souza BASTOS (Author), Silvana Regina Perez ORRICO (Author), Carlos ROSSA JUNIOR (Author)
• Format: Book
• Published: University of São Paulo, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The aim of this study was to evaluate a possible synergism between AGE-RAGE and TLR4 signaling and the role of p38 MAPK and NF-kB signaling pathways on the modulation of the expression of inflammatory cytokines and proliferation of cells from the innate and adaptive immune response. Mater...