High-fat diet-induced obesity causes an inflammatory microenvironment in the kidneys of aging Long-Evans rats

• Main Authors: Thea Laurentius (Author), Ute Raffetseder (Author), Claudia Fellner (Author), Robert Kob (Author), Mahtab Nourbakhsh (Author), Jürgen Floege (Author), Thomas Bertsch (Author), Leo Cornelius Bollheimer (Author), Tammo Ostendorf (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Obesity is a risk factor for chronic kidney disease (CKD). While the exact mechanisms remain unclear, inflammation may be a consequence of obesity that directly impacts the kidneys. The aim of this study was to examine the inflammatory status of the kidneys and potential ongoing...