Transcriptomic profiling of the digestive tract of the rat flea, Xenopsylla cheopis, following blood feeding and infection with Yersinia pestis.

• Main Authors: David M Bland (Author), Craig A Martens (Author), Kimmo Virtaneva (Author), Kishore Kanakabandi (Author), Dan Long (Author), Rebecca Rosenke (Author), Greg A Saturday (Author), Forrest H Hoyt (Author), Daniel P Bruno (Author), José M Ribeiro (Author), B Joseph Hinnebusch (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Yersinia pestis, the causative agent of plague, is a highly lethal pathogen transmitted by the bite of infected fleas. Once ingested by a flea, Y. pestis establish a replicative niche in the gut and produce a biofilm that promotes foregut colonization and transmission. The rat flea Xenopsylla cheopi...