Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer's Mice

• Main Authors: Henning Johannes Drews (Author), Roman Klein (Author), Ali Lourhmati (Author), Marine Buadze (Author), Elke Schaeffeler (Author), Thomas Lang (Author), Torgom Seferyan (Author), Leah R. Hanson (Author), William H. Frey II (Author), Tom C.G.M. de Vries (Author), Inge A.E.W. Thijssen-van Loosdregt (Author), Christoph H. Gleiter (Author), Matthias Schwab (Author), Lusine Danielyan (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiotensin receptor blockers (ARBs) have demonstrated multiple neuroprotective benefits in Alzheimer's disease (AD) models. However, their beneficial effects on memory deficits, cholinergic activity, neurogenesis and Amyloid beta (Aβ) clearance reveal significant interstudy variability. The de...