α-Hispanolol Induces Apoptosis and Suppresses Migration and Invasion of Glioblastoma Cells Likely via Downregulation of MMP-2/9 Expression and p38MAPK Attenuation

• Main Authors: Vanesa Sánchez-Martín (Author), Lidia Jiménez-García (Author), Sandra Herranz (Author), Alfonso Luque (Author), Paloma Acebo (Author), Ángel Amesty (Author), Ana Estévez-Braun (Author), Beatriz de las Heras (Author), Sonsoles Hortelano (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

α-Hispanolol (α-H) is a labdane diterpenoid that has been shown to induce apoptosis in several human cancer cells. However, the effect of α-H in human glioblastoma cells has not been described. In the present work, we have investigated the effects of α-H on apoptosis, migration, and invasion of huma...