NYX-2925, A NOVEL, NON-OPIOID, SMALL-MOLECULE MODULATOR OF THE N-METHYL-d-ASPARTATE RECEPTOR (NMDAR), DEMONSTRATES POTENTIAL TO TREAT CHRONIC, SUPRASPINAL CENTRALIZED PAIN CONDITIONS

• Main Authors: Jessica Marie Gajda, MS (Author), Marina Asiedu, PhD (Author), Gladys Morrison, PhD (Author), Jacqueline Ann Dunning (Author), Nayereh Ghoreishi-Haack, MS (Author), Amanda Lynn Barth, PhD (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pain is both a sensory and emotional experience, which serves an adaptive purpose by protecting the body from prolonged and repeated tissue damage. However, the presence of chronic pain can transition to a maladaptive state leading to life-long suffering and is currently a health care burden due to...