Application of a Deep Eutectic Solvent for the Synthesis of Novel Imidazole-Containing Quinazoline Derivatives as Potent Cytotoxic Agents

• Main Authors: Fatemeh Azmian Moghadam (Author), Sara Dabirian (Author), Amin Ebrahimi Tavani (Author), Parisa Alipour (Author), Mohammad Mojabi (Author), Mehdi Evazalipour (Author), Fatemeh Yousefbeyk (Author), Saeed Ghasemi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Drugs containing the 4-anilinoquinazolines scaffold play a critical role in cancer treatment by inhibiting protein kinases, especially tyrosine kinases. In this study, a novel series of 4-anilinoquinazoline derivatives were synthesized and evaluated as cytotoxic agents. Methods: All fina...