14-3-3ζ mediates an alternative, non-thermogenic mechanism in male mice to reduce heat loss and improve cold tolerance

• Main Authors: Kadidia Diallo (Author), Sylvie Dussault (Author), Christophe Noll (Author), Angel F. Lopez (Author), Alain Rivard (Author), André C. Carpentier (Author), Gareth E. Lim (Author)
• Format: Book
• Published: Elsevier, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adaptive thermogenesis, which is partly mediated by sympathetic input on brown adipose tissue (BAT), is a mechanism of heat production that confers protection against prolonged cold exposure. Various endogenous stimuli, for example, norepinephrine and FGF-21, can also promote the conversi...