Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy

Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this problem, our group constructed an engineered...

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Main Authors: De-Xi Zhou (Author), Xiao-He Wang (Author), Xuan Xu (Author), Wen-Jie Chen (Author), Jing Wei (Author), Ting-Tao Chen (Author), Hong Wei (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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