Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy

• المؤلفون الرئيسيون: De-Xi Zhou (مؤلف), Xiao-He Wang (مؤلف), Xuan Xu (مؤلف), Wen-Jie Chen (مؤلف), Jing Wei (مؤلف), Ting-Tao Chen (مؤلف), Hong Wei (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this problem, our group constructed an engineered...