Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Renoprotective Effects of Aldosterone Blockade

Abstract.: Recent clinical and pre-clinical studies have indicated the utility of mineralocorticoid receptor (MR) antagonists in renal injury. We have demonstrated in rats that chronic treatment with aldosterone results in severe proteinuria and renal injury, characterized by glomerular changes, tub...

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Hoofdauteurs: Akira Nishiyama (Auteur), Youichi Abe (Auteur)
Formaat: Boek
Gepubliceerd in: Elsevier, 2006-01-01T00:00:00Z.
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