Preparation and In Vitro Evaluation of a Gadolinium-Containing Vitamin E TPGS Micelle as a Potential Contrast Agent for MR Imaging

• Main Authors: Yongkang Gai (Author), Yuying Li (Author), Shuangping Wu (Author), Ling Xu (Author), Yao Lu (Author), Xiaoli Lan (Author), Guangya Xiang (Author), Xiang Ma (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The application of many currently evaluated macromolecular contrast agents for magnetic resonance imaging (MRI) has been limited because of their bio-incompatibility and toxicity. The aim of this study is to synthesize and characterize a new micelle-based TPGS gadolinium chelate as a biocompatible M...