Mechanisms of NMDA Receptor Inhibition by Biguanide Compounds

N-methyl-D-aspartate (NMDA) receptors are inhibited by many medicinal drugs. The recent successful repurposing of NMDA receptor antagonists ketamine and dextromethorphan for the treatment of major depressive disorder further enhanced the interest in this field. In this work, we performed a screening...

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Main Authors: Arseniy S. Zhigulin (Author), Anastasiya O. Novikova (Author), Oleg I. Barygin (Author)
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Publicado em: MDPI AG, 2024-09-01T00:00:00Z.
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