Total Triterpenes of Wolfiporia cocos (Schwein.) Ryvarden & Gilb Exerts Antidepressant-Like Effects in a Chronic Unpredictable Mild Stress Rat Model and Regulates the Levels of Neurotransmitters, HPA Axis and NLRP3 Pathway

• Main Authors: Xiang Pan (Author), Kezhuo Chen (Author), Sijie Han (Author), Xinyao Luo (Author), Dandan Zhang (Author), Hanrui Zhang (Author), Lian Zhang (Author), Xuxiang Zhou (Author), Jing Li (Author), Jingxian Fang (Author), Shiqin Wang (Author), Xiaochuan Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose:Wolfiporia cocos is frequently used in traditional Chinese medicine to treat depression. However, antidepressant-like effects of the main active ingredients of Wolfiporia cocos, total triterpenes of Wolfiporia cocos (TTWC), are not well studied. This study aimed to investigate those effects...