Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis

• Main Authors: Kim Landry-Truchon (Author), Nicolas Houde (Author), Mickaël Lhuillier (Author), Louis Charron (Author), Alice Hadchouel (Author), Christophe Delacourt (Author), William D. Foulkes (Author), Louise Galmiche-Rolland (Author), Lucie Jeannotte (Author)
• Format: Book
• Published: The Company of Biologists, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pleuropulmonary blastoma (PPB) is a very rare pediatric lung disease. It can progress from abnormal epithelial cysts to an aggressive sarcoma with poor survival. PPB is difficult to diagnose as it can be confounded with other cystic lung disorders, such as congenital pulmonary airway malformation (C...