Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis

• Ngā kaituhi matua: Kim Landry-Truchon (Author), Nicolas Houde (Author), Mickaël Lhuillier (Author), Louis Charron (Author), Alice Hadchouel (Author), Christophe Delacourt (Author), William D. Foulkes (Author), Louise Galmiche-Rolland (Author), Lucie Jeannotte (Author)
• Hōputu: Pukapuka
• I whakaputaina: The Company of Biologists, 2020-12-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Pleuropulmonary blastoma (PPB) is a very rare pediatric lung disease. It can progress from abnormal epithelial cysts to an aggressive sarcoma with poor survival. PPB is difficult to diagnose as it can be confounded with other cystic lung disorders, such as congenital pulmonary airway malformation (C...