Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells

• Main Authors: Callinice D. Capo-chichi (Author), Jennifer L. Smedberg (Author), Malgorzata Rula (Author), Emmanuelle Nicolas (Author), Anthony T. Yeung (Author), Richard F. Adamo (Author), Andrey Frolov (Author), Andrew K. Godwin (Author), Xiang-Xi Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Mouse embryonic stem (ES) cells can be differentiated in vitro by aggregation and/or retinoic acid (RA) treatment. The principal differentiation lineage in vitro is extraembryonic primitive endoderm. Dab2, Laminin, GATA4, GATA5, and GATA6 are expressed in embryonic primitive endoderm and...