Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD

The role of exosome-mediated mitophagy in the crosstalk between hepatocytes (HCs) and hepatic stellate cells (HSCs) in metabolic-associated fatty liver disease (MAFLD) remains unknown. Serum exosomal miR-27a levels were markedly increased and positively correlated with liver fibrosis in MAFLD patien...

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Main Authors: Xin Luo (Author), Zi-Xin Xu (Author), Jun-Cheng Wu (Author), Sheng-Zheng Luo (Author), Ming-Yi Xu (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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