Prediction of Positions of Active Compounds Makes It Possible To Increase Activity in Fragment-Based Drug Development

• Yazar: Yoshifumi Fukunishi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2011-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We have developed a computational method that predicts the positions of active compounds, making it possible to increase activity as a fragment evolution strategy. We refer to the positions of these compounds as the active position. When an active fragment compound is found, the following lead gener...