Testing the thrifty gene hypothesis: the Gly482Ser variant in <it>PPARGC1A </it>is associated with BMI in Tongans

• Main Authors: Macartney-Coxson Donia P (Author), Engelken Johannes (Author), Hardouin Emilie (Author), Weiss Joerg G (Author), Chambers Geoff K (Author), Ohashi Jun (Author), Lea Rod A (Author), Myles Sean (Author), Eccles David A (Author), Naka Izumi (Author), Kimura Ryosuke (Author), Inaoka Tsukasa (Author), Matsumura Yasuhiro (Author), Stoneking Mark (Author)
• Format: Book
• Published: BMC, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The thrifty gene hypothesis posits that, in populations that experienced periods of feast and famine, natural selection favoured individuals carrying thrifty alleles that promote the storage of fat and energy. Polynesians likely expe...