Anserine and Carnosine Induce HSP70-Dependent H₂S Formation in Endothelial Cells and Murine Kidney

• Main Authors: Charlotte Wetzel (Author), Tilman Pfeffer (Author), Ruben Bulkescher (Author), Johanna Zemva (Author), Sergio Modafferi (Author), Alessandra Polimeni (Author), Angela Trovato Salinaro (Author), Vittorio Calabrese (Author), Claus Peter Schmitt (Author), Verena Peters (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anserine and carnosine have nephroprotective actions; hydrogen sulfide (H₂S) protects from ischemic tissue damage, and the underlying mechanisms are debated. In view of their common interaction with HSP70, we studied possible interactions of both dipeptides with H<sub>2&...