The impact of septic stimuli on the systemic inflammatory response and physiologic insult in a preclinical non-human primate model of polytraumatic injury

• Главные авторы: Diego A. Vicente (Автор), Matthew J. Bradley (Автор), Benjamin Bograd (Автор), Crystal Leonhardt (Автор), Eric A. Elster (Автор), Thomas A. Davis (Автор)
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• Опубликовано: BMC, 2018-05-01T00:00:00Z.
• Предметы: article
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Abstract Background Established animal trauma models are limited in recapitulating the pathophysiology of human traumatic injury. Herein, we characterize the physiologic insult and inflammatory response in two clinically relevant non-human primate (NHP) trauma models. Methods Mauritian Cynomolgus Ma...