Imaging-Based Characterization of a <i>Slco2b1<sup>(-/-)</sup></i> Mouse Model Using [<sup>11</sup>C]Erlotinib and [<sup>99m</sup>Tc]Mebrofenin as Probe Substrates

Imaging-Based Characterization of a <i>Slco2b1<sup>(-/-)</sup></i> Mouse Model Using [<sup>11</sup>C]Erlotinib and [<sup>99m</sup>Tc]Mebrofenin as Probe Substrates

Organic anion-transporting polypeptide 2B1 (OATP2B1) is co-localized with OATP1B1 and OATP1B3 in the basolateral hepatocyte membrane, where it is thought to contribute to the hepatic uptake of drugs. We characterized a novel <i>Slco2b1<sup>(-/-)</sup></i> mouse model using po...

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Main Authors: Solène Marie (Author), Irene Hernández-Lozano (Author), Louise Breuil (Author), Charles Truillet (Author), Shuiying Hu (Author), Alex Sparreboom (Author), Nicolas Tournier (Author), Oliver Langer (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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