Anti-Cancer Activity of As₄O₆ and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer

• Main Authors: Joseph J. Noh (Author), Myeong-Seon Kim (Author), Young-Jae Cho (Author), Soo-Young Jeong (Author), Yoo-Young Lee (Author), Ji-Yoon Ryu (Author), Jung-Joo Choi (Author), Illju Bae (Author), Zhaoyan Wu (Author), Byoung-Gie Kim (Author), Jae Ryoung Hwang (Author), Jeong-Won Lee (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To investigate the anti-cancer effects of tetraarsenic hexoxide (TAO, As₄O₆) in cervical cancer cell lines and in a series of patient-derived xenograft (PDX) mouse models. Methods: Human cervical cancer cell lines, including HeLa, SiHa and CaSki...