Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats

• Main Authors: Jing-Jing Xu (Author), Feng Xu (Author), Wei Wang (Author), Peng-Pu Wang (Author), Jing Xian (Author), Xing Han (Author), Ming-Ying Shang (Author), Guang-Xue Liu (Author), Xuan Wang (Author), Shao-Qing Cai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholestasis is the most destructive pathological manifestation of liver disease and available treatments are very limited. Paeoniae Radix Rubra (PRR) is an important traditional Chinese drug used to treat cholestasis. This study combined targeted metabonomics, PCR array analysis, and 16S rRNA sequen...