MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB
Alzheimer's disease (AD) is characterized by two landmark pathologies, the overproduction of amyloid-beta peptides (Aβ), predominated by the β-amyloid protein precursor cleaving enzyme 1 (BACE1), and hyperphosphorylation of the microtubule protein, tau, because of an imbalance in a kinase/phosp...
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Main Authors: | Linlin Wang (Author), Jianghong Liu (Author), Qian Wang (Author), Hailun Jiang (Author), Li Zeng (Author), Zhuorong Li (Author), Rui Liu (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2019-07-01T00:00:00Z.
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