Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low- to middle-income countries

• Main Authors: Richard M. Gibson (Author), Gabrielle Nickel (Author), Michael Crawford (Author), Fred Kyeyune (Author), Colin Venner (Author), Immaculate Nankya (Author), Eva Nabulime (Author), Emmanuel Ndashimye (Author), Art F. Y. Poon (Author), Robert A. Salata (Author), Cissy Kityo (Author), Peter Mugyenyi (Author), Miguel E. Quiñones-Mateu (Author), Eric J. Arts (Author)
• Format: Book
• Published: BMC, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Thymidine analogs, namely AZT (Zidovudine or Retrovir™) and d4T (Stavudine or Zerit™) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) in Kampala, Uganda despite aversion to prescribing these drugs for cART in high income...