Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish
SUMMARY To assess the effects during cardiac development of mutations that cause human cardiomyopathy, we modeled a sarcomeric gene mutation in the embryonic zebrafish. We designed morpholino antisense oligonucleotides targeting the exon 13 splice donor site in the zebrafish cardiac troponin T (tnnt...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2011-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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