Evaluation of pharmacokinetics and safety of cetuximab with cisplatin/carboplatin in patients with advanced solid tumor: Result from phase II studies

• Main Authors: Raymond P. Perez (Author), Eric Chen (Author), J. Thaddeus Beck (Author), Keisuke Shirai (Author), David Neil Hayes (Author), Tong Shen (Author), John R. Baldwin (Author), Katherine B. Bryant (Author), Shuang He (Author), Steve Chin (Author)
• Format: Book
• Published: Wiley, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The pharmacokinetics and potential drug-drug interactions between cetuximab and cisplatin or carboplatin from two studies (JXBA and JXBB) were evaluated. These studies were multicenter, open‐label phase II trials designed to evaluate the drug-drug interactions between cetuximab (400 mg m−2...