Hydrophobic ion pairing and microfluidic nanoprecipitation enable efficient nanoformulation of a small molecule indolamine 2, 3‐dioxygenase inhibitor immunotherapeutic

Abstract Blockade of programmed cell death‐1 (PD‐1) is a transformative immunotherapy. However, only a fraction of patients benefit, and there is a critical need for broad‐spectrum checkpoint inhibition approaches that both enhance the recruitment of cytotoxic immune cells in cold tumors and target...

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Main Authors: Parisa Badiee (Author), Michelle F. Maritz (Author), Pouya Dehghankelishadi (Author), Nicole Dmochowska (Author), Benjamin Thierry (Author)
Format: Book
Published: Wiley, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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